Novel Cephalosporins Selectively Active on NonreplicatingMycobacterium tuberculosis
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منابع مشابه
Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis
We report two series of novel cephalosporins that are bactericidal to Mycobacterium tuberculosis alone of the pathogens tested, which only kill M. tuberculosis when its replication is halted by conditions resembling those believed to pertain in the host, and whose bactericidal activity is not dependent upon or enhanced by clavulanate, a β-lactamase inhibitor. The two classes of cephalosporins b...
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ژورنال
عنوان ژورنال: Journal of Medicinal Chemistry
سال: 2016
ISSN: 0022-2623,1520-4804
DOI: 10.1021/acs.jmedchem.5b01833